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Guaiacol CAS 90-05-1

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Product Name: Guaiacol
Synonyms: 2-Methoxyphenol/Guaiacol; GAIACOL; 0-Methoxyphenol; 0-Hydroxyanisole; 2-Methoxyphenol; Catechol monomethyl ether; Guaiaco; 1-Hydroxy-2-methoxybenzene; a-methoxyphenolsalicyl methyl ether
Assay: 99.5 Percent
CAS No.: 90-05-1
EINECS No.: 201-964-7
Molecular Formula: C7H8O2
Molecular Weight: 124.14
Density: 1.129 g/mL at 25 Deg(lit.)
Melting point: 26-29 Deg(lit.)
Boiling point: 205 DEG(lit.)
Flashing point: 82DEG
Water Solubillity: 17 g/L (15 DEG)
Appearance: Pale yellow transparent oily liquid
Packing: 25kg/drum
Application: Used in Pharmaceuticals, dye and spices intermediates


Guaiacol is a naturally occurring organic compound with the formula C6H4(OH)(OCH3), discovered by Ascanio Sobrero[citation needed]. Although it is biosynthesized by a variety of organisms, this yellowish aromatic oil is usually derived from guaiacum or wood creosote. Samples darken upon exposure to air and light. Guaiacol is present in wood smoke, resulting from the pyrolysis of lignin. The compound contributes to the flavor of many compounds, e.g., roasted coffee.

Guaiacol is a precursor to various flavorants, such as eugenol and vanillin. Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can be used as an indicator in chemical reactions that produce oxygen. When oxygen binds to it, the complex turns yellowish brown and absorbs light maximally at about 470 nm.